Nasal polyps are noncancerous, soft tissue growths that can develop in the lining of your nasal passages and sinuses. Though benign, these growths can significantly impact your quality of life—causing chronic congestion, sinus infections, facial pressure, and loss of smell. At New York Sinusitis Treatment, Dr. Gregory Levitin, MD, FACS, offers the latest, evidence-based treatment options for patients suffering from nasal polyps in both Manhattan (Columbus Circle) and Williamsburg offices.

Thanks to recent advancements in biologic medications, many patients now have non-surgical options that target the root cause of nasal polyps and reduce the need for repeated sinus surgeries.

What Are Nasal Polyps?

Nasal polyps are typically associated with chronic inflammation and are often seen in patients with:

• Chronic rhinosinusitis with nasal polyps (CRSwNP)
• Asthma
• Aspirin-exacerbated respiratory disease (AERD)
• Allergic fungal sinusitis

They often develop in both nostrils and can obstruct airflow, block sinus drainage, and increase the frequency of sinus infections. Without treatment, they may grow large enough to cause serious breathing difficulties.

Non-Surgical Treatment Options

In the past, many patients with moderate to severe nasal polyps required functional endoscopic sinus surgery (FESS). While surgery is still a vital tool in some cases, new biologic therapies offer a powerful alternative that targets the underlying inflammation, helping to shrink or prevent the regrowth of polyps.

Dupixent (dupilumab)

Dupixent is an FDA-approved injectable biologic therapy that targets interleukin-4 and interleukin-13, two key drivers of inflammation in patients with CRSwNP. It is administered every two weeks and is typically used alongside nasal corticosteroids.

Benefits of Dupixent include:

• Significant reduction in nasal polyp size
• Improvement in sense of smell
• Relief from congestion and pressure
• Decreased sinus infection frequency
• Lower risk of needing revision surgery

In clinical trials, many patients experienced noticeable symptom relief within weeks and continued improvement over several months.

Nucala (mepolizumab)

Nucala is another biologic medication that targets eosinophils, a type of white blood cell involved in allergic inflammation. Originally used to treat eosinophilic asthma, it’s now also approved for patients with CRSwNP who have elevated eosinophil levels and frequent nasal polyps.

Nucala is administered once a month via injection and is particularly helpful in patients with:

• Eosinophilic inflammation
• Coexisting asthma
• Recurrent polyps after surgery

Nucala has been shown to reduce the need for systemic steroids and surgery, while improving nasal obstruction and smell loss.

Other Conservative Treatments

Dr. Levitin also incorporates a multi-tiered approach to managing nasal polyps, which may include:

• Nasal corticosteroid sprays or rinses
• Oral corticosteroids (short-term use)
• Allergy testing and treatment
• Saline irrigations and decongestants
• Asthma management, if relevant

Combining these conservative treatments with biologics can lead to lasting relief and better control of underlying conditions contributing to chronic sinus inflammation.

When Is Surgery Needed?

If medical therapy—including biologics—fails to reduce symptoms, or if polyps are causing significant blockage, endoscopic sinus surgery may still be necessary. Dr. Levitin performs advanced, minimally invasive procedures to remove polyps and restore normal sinus drainage with minimal downtime and discomfort.

Expert Care with a Personalized Approach

Dr. Gregory Levitin, MD, FACS, is a board-certified Otolaryngologist-Head and Neck Surgeon and a Fellow of the American Academy of Otolaryngology–Head and Neck Surgery. As an Assistant Clinical Professor at The New York Eye and Ear Infirmary, he remains on the cutting edge of sinus care, offering the most advanced diagnostics and treatments for both adult and pediatric patients.

Whether you’re exploring biologic therapy, managing post-surgical care, or seeking your first diagnosis, Dr. Levitin’s personalized approach ensures that every patient receives a treatment plan that fits their lifestyle, symptoms, and long-term health goals.

Schedule a Consultation Today

If you’re suffering from nasal congestion, sinus pressure, or recurrent polyps, don’t wait. Relief is possible—without immediate surgery. Contact New York Sinusitis Treatment today to schedule a consultation with Dr. Levitin in Williamsburg or Columbus Circle, and learn how innovative treatment options like Dupixent and Nucala can help you breathe easier and live better.